micro-radiographic system for dynamic high
spatial resolution imaging of living small animals has been developed.
system is based on a micro-focus X-ray tube and the hybrid single
counting silicon pixel detector Medipix2 (matrix 256 x 256 sq. pixels
of 55 µm
pitch). Performance of the system allows real-time observation of inner
in living organisms. However, soft tissue shows a similar value of the
absorption coefficient within the whole volume causing insufficiency of
classical radiographic techniques. We thus decided to adopt a novel
method Phase enhanced imaging. The phase of spatially
coherent X-ray waves passing through an object is shifted according to
effective refractive index. This process causes edge contrast
the obtaine images.
magnification: 1x – 20x
stabilized at 10 and 0°C
voltage 40 – 90
kV, current 70 – 240 uA
energy threshold set to ~5keV
Response of each
pixel calibrated for different attenuator thicknesses
time 100 msec – 30 sec per frame
for X-ray µ-radiography and µ-tomography: µ-focus
X-ray tube, automatic sample
holder and calibration carrousel with images behind.